Exposing the Big Game

Forget Hunters' Feeble Rationalizations and Trust Your Gut Feelings: Making Sport of Killing Is Not Healthy Human Behavior

Exposing the Big Game

Why have 14,000 people volunteered to be infected with coronavirus?

Exposing the Big Game's avatarThe Extinction Chronicles

They want to take part in a “human challenge trial,” an ethically controversial vaccine test that infects people with a virus does not yet have a cure.
Cambridge Biotech Moderna Leads in Race For Coronavirus Vaccine

A scientist works in the lab at Moderna in Cambridge, Mass. on Feb. 28, 2020.David L. Ryan / Boston Globe via Getty Images

By Kit Ramgopal

Imagine being told to inhale a nasal spray full of coronavirus. More than 14,000 people in the U.S. and elsewhere are putting their names forward to do so.

They are volunteering for what’s called a “human challenge trial,” an ethically controversial way to test vaccines that would deliberately infect people with a virus that has killed over 270,000 people worldwide and has no cure.

“It’s not every day we give a healthy individual an exposure to a pathogen — the very same thing doctors are trying to protect people from,” said Dr. Nir Eyal, director of…

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